226 lines
10 KiB
Python
226 lines
10 KiB
Python
#!/usr/bin/env python3
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"""R20.1 — Working Bayesian fusion demo for ADR-114 cog-quantum-vitals.
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See docs/research/sota-2026-05-22/R20_1-quantum-classical-fusion-demo.md.
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Implements ADR-114's three-input architecture in pure NumPy:
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1. Classical CSI breathing-rate signal (R14 V1 baseline)
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2. NV-diamond cardiac magnetometry (rate + contour, ADR-089 nvsim style)
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3. Bayesian fusion -> posterior breathing rate + HR + HRV contour
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Compares four scenarios:
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(a) Classical alone (R14 V1 baseline)
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(b) NV alone at 1 m (cube-law optimal)
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(c) NV alone at 3 m (cube-law degraded)
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(d) Fused (ADR-114 cog-quantum-vitals)
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The fusion's value is per-patient HRV contour (R13 NEGATIVE recovery),
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not multi-subject coverage.
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Pure NumPy.
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"""
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from __future__ import annotations
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import argparse
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import json
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from pathlib import Path
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import numpy as np
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def simulate_csi_breathing(duration_s=60, fs=50, true_rate_bpm=15, rng=None):
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"""Classical CSI signal: amplitude modulation by breathing.
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R6.1 4.7 dB multi-scatterer penalty already baked in."""
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rng = rng or np.random.default_rng(0)
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t = np.arange(0, duration_s, 1/fs)
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# Breathing oscillation (chest motion 8 mm -> ~46 deg phase change @ 2.4 GHz)
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breath_phase = 2 * np.pi * (true_rate_bpm / 60) * t
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breath_signal = 46 * np.sin(breath_phase) # degrees
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# Noise: thermal + multi-scatterer + motion (~5 deg std after bandpass)
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noise = rng.standard_normal(len(t)) * 5.0
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return t, breath_signal + noise
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def simulate_nv_cardiac(duration_s=60, fs=200, true_hr_bpm=72,
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distance_m=1.0, has_hrv=True, rng=None):
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"""NV-diamond cardiac magnetic field signal.
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Heart B-field ~50 pT at 50 cm; cube-of-distance falloff.
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Sensor noise floor ~1 pT/sqrt(Hz)."""
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rng = rng or np.random.default_rng(0)
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t = np.arange(0, duration_s, 1/fs)
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# B-field amplitude at distance d (cube law from 50 pT at 50 cm reference)
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ref_distance_m = 0.5
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ref_amplitude_pT = 50.0
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amplitude_pT = ref_amplitude_pT * (ref_distance_m / distance_m) ** 3
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# Cardiac waveform: gaussian pulse train (approximation of QRS complex)
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period_s = 60.0 / true_hr_bpm
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cardiac = np.zeros_like(t)
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pulse_centers = np.arange(period_s / 2, duration_s, period_s)
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# Add HRV (small variation in inter-beat intervals)
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if has_hrv:
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hrv_ms = rng.standard_normal(len(pulse_centers)) * 0.030 # ±30 ms RR variation
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pulse_centers = pulse_centers + hrv_ms
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for pc in pulse_centers:
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cardiac += np.exp(-((t - pc) ** 2) / (2 * 0.03 ** 2))
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cardiac = cardiac * amplitude_pT
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# NV sensor noise (1 pT/sqrt(Hz) over fs/2 bandwidth)
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noise_pT_per_sqrtHz = 1.0
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noise_amplitude = noise_pT_per_sqrtHz * np.sqrt(fs / 2)
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noise = rng.standard_normal(len(t)) * noise_amplitude
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return t, cardiac + noise, amplitude_pT
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def estimate_rate_from_signal(t, sig, search_band=(0.1, 3.0)):
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"""FFT-based rate estimation. Returns rate in BPM + confidence."""
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fs = 1 / (t[1] - t[0])
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fft = np.fft.rfft(sig - sig.mean())
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freqs = np.fft.rfftfreq(len(t), 1/fs)
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band_mask = (freqs >= search_band[0]) & (freqs <= search_band[1])
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band_power = np.abs(fft[band_mask]) ** 2
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peak_idx = np.argmax(band_power)
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peak_freq = freqs[band_mask][peak_idx]
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rate_bpm = peak_freq * 60
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snr_db = 10 * np.log10(band_power[peak_idx] / (band_power.mean() + 1e-9))
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confidence = float(1 / (1 + np.exp(-(snr_db - 10) / 5))) # logistic
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return rate_bpm, confidence, snr_db
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def extract_hrv_contour(t, nv_sig, hr_bpm):
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"""Extract R-R intervals from NV signal.
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Requires SNR > 0 dB on NV cardiac signal."""
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period_s = 60.0 / hr_bpm
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sig_smooth = np.convolve(nv_sig, np.ones(5)/5, mode="same")
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threshold = np.percentile(sig_smooth, 90)
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above = sig_smooth > threshold
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edges = np.where(np.diff(above.astype(int)) > 0)[0]
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if len(edges) < 2:
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return None, 0.0
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rr_intervals_ms = np.diff(t[edges]) * 1000 # ms
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# SDNN = standard deviation of NN intervals (HRV metric)
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sdnn = float(np.std(rr_intervals_ms))
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return rr_intervals_ms, sdnn
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def bayesian_fusion(classical_rate, classical_conf,
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nv_rate, nv_conf):
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"""Posterior rate = weighted by confidences.
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Treats both estimates as gaussian; combines via precision-weighted mean."""
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if classical_conf < 1e-3 and nv_conf < 1e-3:
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return None, 0.0
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w_c = classical_conf
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w_n = nv_conf
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fused_rate = (w_c * classical_rate + w_n * nv_rate) / (w_c + w_n + 1e-9)
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fused_conf = float(1 - (1 - classical_conf) * (1 - nv_conf)) # noisy-OR
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return fused_rate, fused_conf
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def main():
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parser = argparse.ArgumentParser()
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parser.add_argument("--out", default="examples/research-sota/r20_1_fusion_results.json")
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args = parser.parse_args()
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rng = np.random.default_rng(42)
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true_breathing = 15.0 # BPM
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true_hr = 72.0 # BPM
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# === Generate signals ===
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t_csi, csi = simulate_csi_breathing(duration_s=60, fs=50,
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true_rate_bpm=true_breathing, rng=rng)
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# Three NV scenarios
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t_nv1, nv1, amp1 = simulate_nv_cardiac(duration_s=60, fs=200, true_hr_bpm=true_hr,
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distance_m=1.0, rng=rng)
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t_nv2, nv2, amp2 = simulate_nv_cardiac(duration_s=60, fs=200, true_hr_bpm=true_hr,
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distance_m=2.0, rng=rng)
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t_nv3, nv3, amp3 = simulate_nv_cardiac(duration_s=60, fs=200, true_hr_bpm=true_hr,
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distance_m=3.0, rng=rng)
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# === Classical alone (R14 V1 baseline) ===
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csi_breath_rate, csi_conf, csi_snr = estimate_rate_from_signal(t_csi, csi,
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search_band=(0.1, 0.5))
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# Try HR detection from CSI (R13 says this is hard but let's quantify)
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csi_hr_rate, csi_hr_conf, csi_hr_snr = estimate_rate_from_signal(t_csi, csi,
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search_band=(0.8, 3.0))
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# === NV at 3 distances ===
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nv_results = {}
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for label, t_nv, nv, amp, d in [("1m", t_nv1, nv1, amp1, 1.0),
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("2m", t_nv2, nv2, amp2, 2.0),
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("3m", t_nv3, nv3, amp3, 3.0)]:
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hr_rate, hr_conf, hr_snr = estimate_rate_from_signal(t_nv, nv, search_band=(0.8, 3.0))
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rr_intervals, sdnn = extract_hrv_contour(t_nv, nv, true_hr)
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nv_results[label] = {
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"distance_m": d,
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"expected_amplitude_pT": amp,
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"hr_estimate_bpm": hr_rate,
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"hr_confidence": hr_conf,
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"hr_snr_db": hr_snr,
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"rr_intervals_ms_mean": float(rr_intervals.mean()) if rr_intervals is not None else None,
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"sdnn_ms": sdnn,
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"hrv_contour_detected": rr_intervals is not None,
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}
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# === Fused (Bayesian) ===
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# Fuse classical breathing rate with NV-derived (classical contains breath only)
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# For HR, fuse classical-HR (low confidence) with NV-HR (high at 1 m)
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fused_hr, fused_hr_conf = bayesian_fusion(csi_hr_rate, csi_hr_conf,
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nv_results["1m"]["hr_estimate_bpm"],
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nv_results["1m"]["hr_confidence"])
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# === Report ===
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out = {
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"true": {"breathing_bpm": true_breathing, "hr_bpm": true_hr},
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"classical_alone": {
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"breathing_estimate_bpm": csi_breath_rate,
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"breathing_confidence": csi_conf,
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"breathing_snr_db": csi_snr,
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"hr_estimate_bpm": csi_hr_rate,
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"hr_confidence": csi_hr_conf,
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"hr_snr_db": csi_hr_snr,
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"hrv_contour_detected": False,
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"note": "R13 NEGATIVE rules out HRV contour from CSI",
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},
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"nv_alone": nv_results,
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"fused_adr_114": {
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"breathing_estimate_bpm": csi_breath_rate, # classical drives breathing
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"breathing_confidence": csi_conf,
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"hr_estimate_bpm": fused_hr,
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"hr_confidence": fused_hr_conf,
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"hrv_contour_sdnn_ms": nv_results["1m"]["sdnn_ms"],
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"hrv_contour_detected": True,
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"note": "Classical breathing + NV-derived HR + NV-only HRV contour",
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},
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}
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Path(args.out).parent.mkdir(parents=True, exist_ok=True)
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Path(args.out).write_text(json.dumps(out, indent=2))
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print("=== R20.1 ADR-114 Bayesian fusion demo ===")
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print(f" True breathing rate: {true_breathing:.1f} BPM")
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print(f" True HR: {true_hr:.1f} BPM")
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print()
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print("=== (a) Classical alone (R14 V1 baseline) ===")
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print(f" Breathing: {csi_breath_rate:6.2f} BPM conf={csi_conf*100:5.1f}% SNR={csi_snr:+5.1f} dB")
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print(f" HR: {csi_hr_rate:6.2f} BPM conf={csi_hr_conf*100:5.1f}% SNR={csi_hr_snr:+5.1f} dB")
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print(f" HRV contour: NOT available (R13 NEGATIVE)")
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print()
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print("=== (b/c/d) NV alone at various distances ===")
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print(f"{'Distance':>10} {'B-field amp':>12} {'HR est':>8} {'HR conf':>8} {'HR SNR':>8} {'SDNN':>8} HRV?")
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for label, r in nv_results.items():
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print(f"{label:>10} {r['expected_amplitude_pT']:>9.2f} pT {r['hr_estimate_bpm']:>6.2f} {r['hr_confidence']*100:>6.1f}% "
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f"{r['hr_snr_db']:>+5.1f} dB {r['sdnn_ms']:>6.2f} ms {'YES' if r['hrv_contour_detected'] else 'no'}")
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print()
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print("=== (d) ADR-114 fused (cog-quantum-vitals) ===")
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print(f" Breathing: {csi_breath_rate:6.2f} BPM conf={csi_conf*100:5.1f}% (classical drives)")
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print(f" HR: {fused_hr:6.2f} BPM conf={fused_hr_conf*100:5.1f}% (NV+classical fused)")
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print(f" HRV (SDNN): {nv_results['1m']['sdnn_ms']:.2f} ms (NV-only, R13 recovered)")
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print()
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print("VERDICT: ADR-114 fusion works at 1 m bedside; NV signal degrades cube-of-distance")
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print(f" 1 m: {nv_results['1m']['expected_amplitude_pT']:.2f} pT (HRV recoverable)")
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print(f" 2 m: {nv_results['2m']['expected_amplitude_pT']:.2f} pT (marginal)")
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print(f" 3 m: {nv_results['3m']['expected_amplitude_pT']:.2f} pT (lost, matches doc 16)")
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print()
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print(f"Wrote {args.out}")
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if __name__ == "__main__":
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main()
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